Overview

  • Product nameAnti-BRCC2 antibody
  • Description
    Mouse monoclonal to BRCC2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 2-109 of Human BRCC2

Properties

Applications

Our Abpromise guarantee covers the use of ab57813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionFunctions as a proapoptotic molecule through the caspase-dependent mitochondrial pathway of cell death.
    • Tissue specificityUbiquitously expressed.
    • Cellular localizationCytoplasm. Mitochondrion. Lower abundance in mitochondrion than in cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • BH3-like motif containing, cell death inducer antibody
      • BH3-like motif-containing cell death inducer antibody
      • BLID antibody
      • BLID_HUMAN antibody
      • BRCC2 antibody
      • breast cancer cell 2 antibody
      • Breast cancer cell protein 2 antibody
      see all

    Anti-BRCC2 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57813 BRCC2 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    References for Anti-BRCC2 antibody (ab57813)

    This product has been referenced in:
    • Li X  et al. BRCC2 inhibits breast cancer cell growth and metastasis in vitro and in vivo via downregulating AKT pathway. Cell Death Dis 4:e757 (2013). Read more (PubMed: 23928696) »

    See 1 Publication for this product

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"