General notesab94204 is a 293T cell transfected lysate in which Human BRDG 1 has been transiently over-expressed using a pCMV-BRDG 1 plasmid. The lysate is provided in 1 x Sample Buffer. Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundFunction: In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC.
Similarity: Contains 1 PH domain.
Contains 1 SH2 domain.
PTM: Phosphorylated on tyrosine by TEC.