Overview

  • Product nameAnti-BRF1 antibody
    See all BRF1 primary antibodies
  • Description
    Rabbit polyclonal to BRF1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 627 and 677 of human BRF1 (NP_001510.2).

  • Positive control
    • Human Anaplastic Thyroid Carcinoma, Bladder Cell Carcinoma and Prostate Carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionGeneral activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.
    • Sequence similaritiesBelongs to the TFIIB family.
      Contains 1 TFIIB-type zinc finger.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • B related factor 1 antibody
      • B-related factor 1 antibody
      • BRF antibody
      • BRF-1 antibody
      • brf1 antibody
      • BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) antibody
      • General transcription factor IIIB, 90kD subunit antibody
      • GTF3B antibody
      • hBRF antibody
      • hTFIIIB90 antibody
      • RNA polymerase III antibody
      • subunit 2 antibody
      • TAF3B2 antibody
      • TAF3C antibody
      • TAFIII90 antibody
      • TATA box binding protein (TBP) associated factor 3C antibody
      • TATA box binding protein (TBP) associated factor, RNA polymerase III, GTF3B subunit 2 antibody
      • TATA box-binding protein-associated factor antibody
      • TBP associated factor, RNA polymerase III, 90kD antibody
      • TF3B_HUMAN antibody
      • TF3B90 antibody
      • TFIIIB90 antibody
      • Transcription factor IIIB 90 kDa subunit antibody
      • Transcription initiation factor IIIB antibody
      see all

    Anti-BRF1 antibody images

    • ab84560, at a 1/100 dilution, staining BRF1 in formalin fixed, paraffin embedded human prostate carcinoma by Immunohistochemistry, using DAB detection.
    • ab84560, at a 1/500 dilution, staining BRF1 in formalin fixed, paraffin embedded human thyroid carcinoma by Immunohistochemistry, using DAB detection.

    References for Anti-BRF1 antibody (ab84560)

    ab84560 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84560.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"