Overview

  • Product nameBRL 52537 hydrochloride
  • Description
    Highly selective, potent κ-opioid agonist
  • Biological descriptionHighly selective and potent κ-opioid agonist (Ki = 0.24 nM). 25 times more potent than morphine. Neuroprotective effects seen in vivo.
  • Purity> 99%

Properties

    References for BRL 52537 hydrochloride (ab120669)

    This product has been referenced in:
    • Su X  et al. The effect of kappa-opioid receptor agonists on tetrodotoxin-resistant sodium channels in primary sensory neurons. Anesth Analg 109:632-40 (2009). Read more (PubMed: 19608841) »
    • Chen TY  et al. Prolonged opportunity for ischemic neuroprotection with selective kappa-opioid receptor agonist in rats. Stroke 35:1180-5 (2004). Read more (PubMed: 15031456) »
    • Vecchietti V  et al. (2S)-1-(arylacetyl)-2-(aminomethyl)piperidine derivatives: novel, highly selective kappa opioid analgesics. J Med Chem 34:397-403 (1991). Read more (PubMed: 1846921) »

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    Unfortunately as we do not currently undertake our own research we are only able to offer information that is currently available in the literature. It appears that BRL 52537 is used most commonly at 1mg/kg/h, gi...

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