Overview

  • Product nameBRL 54443
  • Description
    Selective agonist at 5-HT1E and 5-HT1F receptors
  • Biological descriptionPotent, high affinity and selective agonist at 5-HT1E/1F receptors (pKi values are 8.7 and 8.9, respectively). Displays >30-fold selectivity for human 5-HT over dopamine receptors (pKi values are 7.2 (5-HT1A), 6.9 (5-HT1B), 7.2 (5-HT1D), 5.9 (5-HT2A), 7.0 (5-HT2B), 6.5 (5-HT2C), 6.3 (D2) and 6.2 (D3)).
  • Purity> 99%

Properties

  • Chemical name5-Hydroxy-3-(1-methylpiperidin-4-yl)-1H-indole
  • Molecular weight230.31
  • Chemical structureChemical Structure
  • Molecular formulaC14H18N2O
  • CAS Number57477-39-1
  • PubChem identifier2438
  • Storage instructionsStore at +4°C. Store under Desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overviewSoluble in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESCN1CCC(CC1)c2cnc3ccc(O)cc23
  • Source

    Synthetic

  • Research areas

    References for BRL 54443 (ab120627)

    ab120627 has not yet been referenced specifically in any publications.

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