Overview

  • Product name
    BRL 54443
  • Description
    Selective agonist at 5-HT1E and 5-HT1F receptors
  • Biological description
    Potent, high affinity and selective agonist at 5-HT1E/1F receptors (pKi values are 8.7 and 8.9, respectively). Displays >30-fold selectivity for human 5-HT over dopamine receptors (pKi values are 7.2 (5-HT1A), 6.9 (5-HT1B), 7.2 (5-HT1D), 5.9 (5-HT2A), 7.0 (5-HT2B), 6.5 (5-HT2C), 6.3 (D2) and 6.2 (D3)).
  • Purity
    > 99%

Properties

  • Chemical name
    5-Hydroxy-3-(1-methylpiperidin-4-yl)-1H-indole
  • Molecular weight
    230.31
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C14H18N2O
  • CAS Number
    57477-39-1
  • PubChem identifier
    2438
  • Storage instructions
    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    CN1CCC(CC1)c2cnc3ccc(O)cc23
  • Source

    Synthetic

  • Research areas

    References for BRL 54443 (ab120627)

    ab120627 has not yet been referenced specifically in any publications.

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