Overview

  • Product name
  • Description
    Rabbit polyclonal to BRN4
  • Specificity
    ab23339 reacts with BRN4.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Dog
  • Immunogen

    A region within synthetic peptide: DSLQLEKEVV RVWFCNRRQK EKRMTPPGDQ QPHEVYSHTV KTDTSCHDL, corresponding to C terminal amino acids 313-361 of Human BRN4

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab23339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1.5625e+006.
WB Use a concentration of 0.3 - 0.5 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 39 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.
  • Tissue specificity
    Brain specific.
  • Involvement in disease
    Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) [MIM:304400]. A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.
  • Sequence similarities
    Belongs to the POU transcription factor family. Class-3 subfamily.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 POU-specific domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Brain specific homeobox POU domain protein 4 antibody
    • Brain-4 antibody
    • Brain-specific homeobox/POU domain protein 4 antibody
    • BRAIN4 antibody
    • Brn-4 antibody
    • BRN4 antibody
    • class 3 antibody
    • DFN3 antibody
    • DFNX2 antibody
    • Oct-9 antibody
    • Octamer-binding protein 9 antibody
    • Octamer-binding transcription factor 9 antibody
    • OTF-9 antibody
    • OTF9 antibody
    • PO3F4_HUMAN antibody
    • POU class 3 homeobox 4 antibody
    • POU domain antibody
    • POU domain class 3 transcription factor 4 antibody
    • Pou3f4 antibody
    • transcription factor 4 antibody
    see all

Images

  • Anti-BRN4 antibody (ab23339) at 0.4 µg/ml + HepG2 whole cell lysate (ab7900) with 5% skim milk/PBS buffer

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) (ab6721)

    Predicted band size : 39 kDa

References

ab23339 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab23339.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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