Anti-Brugia malayi Filaria antibody [WES-7] (ab60294)

Overview

  • Product nameAnti-Brugia malayi Filaria antibody [WES-7]
  • Description
    Mouse monoclonal [WES-7] to Brugia malayi Filaria
  • Specificityab60294 reacts with Brugia malayi Filaria.
  • Tested applicationsSuitable for: ELISA, WB, IHC-Frmore details
  • Species reactivity
    Reacts with
  • Immunogen

    Native. ES protein.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone numberWES-7
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab60294 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IHC-Fr
  • Application notesELISA: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceBrugia malayi is a filarial roundworm found in tropical regions of Asia. It causes filariasis in humans. Worms are spread by mosquitos. An infected mosquito introduces third-stage filarial larvae onto the skin of the human host, where they penetrate into the bite wound and develop into adults that commonly reside in the lymphatics, where they can block lymphatic drainage. Adults produce microfilariae which migrate into lymph and enter the blood stream reaching the peripheral blood. A mosquito ingests the microfilariae during a blood meal. After ingestion, the microfilariae work their way through the wall of the proventriculus and cardiac portion of the midgut to reach the thoracic muscles, where they develop into first-stage larvae and subsequently into third-stage larvae. The third-stage larvae migrate through the hemocoel to the mosquito's prosbocis and can infect another human when the mosquito takes a blood meal.

    References for Anti-Brugia malayi Filaria antibody [WES-7] (ab60294)

    ab60294 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your inquiry. I heard back from the testing laboratory that they have not epitope mapped this antibody. We do know that it recognizes primarily a 58 KDa protein that is broadly distributed throughout the cuticle and hypodermis of adult...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"