Overview

  • Product name
    Anti-BRUNOL5 antibody
  • Description
    Goat polyclonal to BRUNOL5
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide: C-

    EPPGGQPDGMKD

    , corresponding to amino acids 30-41 of Human BRUNOL5 (NP_068757.2)

  • Positive control
    • Human heart lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab77343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/1000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 52 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
    • Tissue specificity
      Expressed in brain.
    • Sequence similarities
      Belongs to the CELF/BRUNOL family.
      Contains 3 RRM (RNA recognition motif) domains.
    • Cellular localization
      Nucleus. Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Bruno like 5, RNA binding protein (Drosophila) antibody
      • Bruno like protein 5 antibody
      • Bruno-like protein 5 antibody
      • BRUNOL 5 antibody
      • CELF 5 antibody
      • CELF-5 antibody
      • CELF5 antibody
      • CELF5_HUMAN antibody
      • CUG BP and ETR 3 like factor 5 antibody
      • CUG-BP- and ETR-3-like factor 5 antibody
      • CUGBP Elav-like family member 5 antibody
      • CUGBP, Elav-like family member 5 antibody
      • RNA binding protein BRUNOL5 antibody
      • RNA-binding protein BRUNOL-5 antibody
      see all

    Images

    References

    ab77343 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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