Overview

  • Product nameAnti-BRUNOL6 antibody
    See all BRUNOL6 primary antibodies
  • Description
    Rabbit polyclonal to BRUNOL6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat
  • Immunogen

    A synthetic peptide corresponding to a region of Human BRUNOL6.

  • Positive control
    • HepG2 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab80314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
  • Tissue specificityExpressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney.
  • Sequence similaritiesBelongs to the CELF/BRUNOL family.
    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localizationNucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 6330569O16Rik antibody
    • Bruno like 6, RNA binding protein (Drosophila) antibody
    • bruno like 6, RNA binding protein antibody
    • Bruno like protein 6 antibody
    • Bruno-like protein 6 antibody
    • CELF-6 antibody
    • Celf6 antibody
    • CELF6_HUMAN antibody
    • CUG-BP- and ETR-3-like factor 6 antibody
    • CUGBP and ETR3 like factor 6 antibody
    • CUGBP Elav-like family member 6 antibody
    • RNA binding protein BRUNOL 6 antibody
    • RNA-binding protein BRUNOL-6 antibody
    see all

Anti-BRUNOL6 antibody images

  • Anti-BRUNOL6 antibody (ab80314) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 50 kDa
    Observed band size : 50 kDa
    Additional bands at : 31 kDa. We are unsure as to the identity of these extra bands.

References for Anti-BRUNOL6 antibody (ab80314)

ab80314 has not yet been referenced specifically in any publications.

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