Overview

  • Product name
    Buspirone hydrochloride
  • Description
    5-HT1A agonist. Anxiolytic.
  • Biological description
    5-HT1A partial agonist (Ki = 9.3 - 29.5 nM). Anxiolytic in vivo. Many reported effects including actions on dopaminergic and noradrenergic pathways, as well as the GABA-benzodiazepine receptor chloride ionophore complex.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Jahanshahi A  et al. Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats. Neurosci Lett 473:136-40 (2010). Read more (PubMed: 20178829) »
  • Eison AS & Temple DL Buspirone: review of its pharmacology and current perspectives on its mechanism of action. Am J Med 80:1-9 (1986). Read more (PubMed: 2870639) »
  • Skolnick P  et al. Preclinical pharmacology of buspirone hydrochloride. Pharmacotherapy 4:308-14 (0). Read more (PubMed: 6151169) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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