Anti-Butyrylcholinesterase antibody (ab82307)

Overview

  • Product nameAnti-Butyrylcholinesterase antibody
    See all Butyrylcholinesterase primary antibodies
  • Description
    Rabbit polyclonal to Butyrylcholinesterase
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to an internal region of Human Butyrylcholinesterase, conjugated to KLH

  • Positive control
    • A2058 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab82307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 68 kDa.
ELISA 1/1000.

Target

  • FunctionEsterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
  • Tissue specificityDetected in blood plasma (at protein level). Present in most cells except erythrocytes.
  • Involvement in diseaseDefects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait.
  • Sequence similaritiesBelongs to the type-B carboxylesterase/lipase family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acylcholine acylhydrolase antibody
    • BCHE antibody
    • Butyrylcholine esterase antibody
    • CHE1 antibody
    • CHE2 antibody
    • CHLE_HUMAN antibody
    • Choline esterase II antibody
    • Cholinesterase (serum) 2 antibody
    • Cholinesterase 1 antibody
    • Cholinesterase antibody
    • E1 antibody
    • Pseudocholinesterase antibody
    • Pseudocholinesterase E1 antibody
    see all

Anti-Butyrylcholinesterase antibody images

  • Anti-Butyrylcholinesterase antibody (ab82307) at 1/50 dilution + A2058 cell line lysate at 35 µg

    Predicted band size : 68 kDa
    Observed band size : 68 kDa
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Butyrylcholinesterase antibody (ab82307)

ab82307 has not yet been referenced specifically in any publications.

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The BCHE antibody, ab82307is generated from rabbits immunized with a KLH conjugated synthetic peptide between ********* amino acids from the center region of human BCHE.

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