Overview

  • Product nameAnti-BVES antibody
    See all BVES primary antibodies
  • Description
    Mouse monoclonal to BVES
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: YSLNDPTLND KKAKKLEHQL SLCTQISMLE MRNSIASSSD SDDGLHQFLR GTSSMSSLHV SSPHQRASAK MKPIEEGAED DDDVFEPASP NTLKVHQLP, corresponding to amino acids 262-361 of Human BVES

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56814 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading.
    • Tissue specificityExpressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle.
    • Sequence similaritiesBelongs to the popeye family.
    • Cellular localizationLateral cell membrane. Cell junction > tight junction. Membrane. Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells.
    • Information by UniProt
    • Database links
    • Alternative names
      • Blood vessel epicardial substance antibody
      • Bves antibody
      • hBVES antibody
      • MGC42413 antibody
      • POP 1 antibody
      • POP1 antibody
      • POPD1_HUMAN antibody
      • POPDC 1 antibody
      • POPDC1 antibody
      • Popeye domain containing 1 antibody
      • Popeye domain containing protein 1 antibody
      • Popeye domain-containing protein 1 antibody
      • Popeye protein 1 antibody
      see all

    Anti-BVES antibody images



    • Predicted band size : 41 kDa
      BVES antibody (ab56814) at 1ug/lane + IMR-32 cell lysate at 25ug/lane.

    References for Anti-BVES antibody (ab56814)

    ab56814 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab56814.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"