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Storage instructions Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage buffer PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purity Tissue culture supernatant
Clone number EPR718(2)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. PubMed: 22569827
1/1000 - 1/10000. Predicted molecular weight: 72 kDa.
Application notes Is unsuitable for Flow Cyt,ICC or IP.
Function Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Sequence similarities Contains 3 HTH myb-type DNA-binding domains.
Domain Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.
Post-translational modifications Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.
Cellular localization Nucleus.
Information by UniProt
C myb antibody
c myb protein (140 AA) antibody
c-myb protein (140 AA) antibody
Anti-c-Myb antibody [EPR718(2)] images
References for Anti-c-Myb antibody [EPR718(2)] (ab109127)
This product has been referenced in:
et al. TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis. Oncogene N/A:N/A (2014).
Read more (PubMed: 24469049) »
et al. GFI1B, EVI5, MYB-Additional genes that cooperate with the human BCL6 gene to promote the development of lymphomas. Blood Cells Mol Dis N/A:N/A (2013).
Read more (PubMed: 23910958) »
See all 3 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"