Overview

  • Product nameAnti-C Reactive Protein antibody [C5]
    See all C Reactive Protein primary antibodies
  • Description
    Mouse monoclonal [C5] to C Reactive Protein
  • SpecificityHuman CRP Specific antibody titer in ELISA is > 10 to the power of -6
  • Tested applicationsSuitable for: ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human).

  • General notes

    Detects CRP in the presence and absence of Ca2+.

Properties

Applications

Our Abpromise guarantee covers the use of ab8279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [C6] to C Reactive Protein (ab8278). Capture
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [C6] to C Reactive Protein (ab8278).

Target

  • FunctionDisplays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • Tissue specificityFound in plasma.
  • Sequence similaritiesBelongs to the pentaxin family.
    Contains 1 pentaxin domain.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Pentraxin 1, short antibody
    • C reactive protein antibody
    • C reactive protein pentraxin related antibody
    • C-reactive protein(1-205) antibody
    • CRP antibody
    • CRP_HUMAN antibody
    • MGC88244 antibody
    • Pentraxin 1 antibody
    • PTX 1 antibody
    • PTX1 antibody
    see all

References for Anti-C Reactive Protein antibody [C5] (ab8279)

This product has been referenced in:
  • Skogstrand K  et al. Effects of blood sample handling procedures on measurable inflammatory markers in plasma, serum and dried blood spot samples. J Immunol Methods 336:78-84 (2008). Read more (PubMed: 18495149) »

See 1 Publication for this product

Product Wall


I have confirmed with the lab and most of our C Reactive Protein antibodies, except C3 and C4, react with both monomer and pentamer form of CRP. (As our clones C3 and C4 do not recognize CRP in the absence of Ca2+ ions, we suggest that they could ...

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Thank you for your enquiry.

I can confirm that ab24462 can be paired for ELISA with http://www.abcam.com/index.html?datasheet=8279 and http://www.abcam.com/index.html?datasheet=8280 so our Abguarantee applies to these products. I regret to in...

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Thank you for your enquiry.

I can confirm that ab24462 can be paired for ELISA with http://www.abcam.com/index.html?datasheet=8279 and http://www.abcam.com/index.html?datasheet=8280 so our Abguarantee applies to these products. Unfortunately,...

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Thank you for contacting us.
We do not use the terminology C number. These does not depicts any information other the clone numbers for a particular antibody.
The sELISA pairs we recommend are
The best pair is C2-C6 (ab24461 detection - ...

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Our antibodies to CRP (clones C2 and C6) are strongly specific to CRP molecule and form a unique two-site combination for the development of fast and sensitive CRP assay. Mabs are not sensitive to the presence of Ca2+- binding reagents in the sample an...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"