FunctionDisplays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Tissue specificityFound in plasma.
Sequence similaritiesBelongs to the pentaxin family. Contains 1 pentaxin domain.
References for Anti-C Reactive Protein antibody (HRP) (ab19175)
This product has been referenced in:
Hamon Y et al. Proteolytic cleavage of the long pentraxin PTX3 in the airways of cystic fibrosis patients. Innate Immun19:611-22 (2013).
Read more (PubMed: 23475792) »
Trilok-Kumar G et al. Effect of vitamin D supplementation of low birth weight term Indian infants from birth on cytokine production at 6 months. Eur J Clin Nutr66:746-50 (2012).
Read more (PubMed: 22510791) »