Overview

  • Product name
    Anti-C12orf48 antibody - C-terminal
    See all C12orf48 primary antibodies
  • Description
    Rabbit polyclonal to C12orf48 - C-terminal
  • Tested applications
    Suitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, between amino acids 529-558 from the C terminal region of Human C12orf48 (NP_060385.3).

  • Positive control
    • WB: A549 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab107308 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab107308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 5 µg/ml.
WB 1/100 - 1/500. Predicted molecular weight: 65 kDa.

Target

  • Function
    May be involved in RNA metabolism. Binds single-strand DNA and poly(A) homopolymers (By similarity). Positively regulate the poly(ADP-ribosyl)ation activity of PARP1.
  • Tissue specificity
    Restricted to testis. Overexpressed in multiple cancer cells.
  • Sequence similarities
    Belongs to the PARP1BP family.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AROM antibody
    • C12orf48 antibody
    • Chromosome 12 open reading frame 48 antibody
    • FLJ20641 antibody
    • PARP 1 binding protein antibody
    • PARP-1 binding protein antibody
    • PARP1 binding protein antibody
    • PARP1-binding protein antibody
    • PARPBP antibody
    • PR1BP_HUMAN antibody
    see all

Images

  • Anti-C12orf48 antibody - C-terminal (ab107308) at 1/100 dilution + A549 cell line lysate at 35 µg

    Predicted band size : 65 kDa

References

This product has been referenced in:
  • Hampp S  et al. DNA damage tolerance pathway involving DNA polymerase ? and the tumor suppressor p53 regulates DNA replication fork progression. Proc Natl Acad Sci U S A 113:E4311-9 (2016). WB ; Human . Read more (PubMed: 27407148) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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