Overview

  • Product name
  • Description
    Rabbit polyclonal to C17orf81
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide within residues: AVSHQDSCPG DSSSVGKVSV LGLLHEELHG PGPVGALSSL AQTEVTLGGT , corresponding to internal sequence amino acids 144-193 of Human C17orf81 (NP_056177)

  • Positive control
    • Human fetal pancreas lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab87175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation.
  • Tissue specificity
    Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis.
  • Sequence similarities
    Belongs to the ELP5 family.
  • Cellular localization
    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • chromosome 17 open reading frame 81 antibody
    • Dermal papilla derived protein 6 antibody
    • Dermal papilla-derived protein 6 antibody
    • DERP6 antibody
    • Elongator acetyltransferase complex subunit 5 antibody
    • Elongator complex protein 5 antibody
    • ELP5 antibody
    • ELP5_HUMAN antibody
    • HSPC002 antibody
    • MST071 antibody
    • MSTP071 antibody
    • S phase 2 protein antibody
    • S-phase 2 protein antibody
    see all

Anti-C17orf81 antibody images

  • Anti-C17orf81 antibody (ab87175) at 1 µg/ml + Human fetal pancreas lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa
    Additional bands at : 32 kDa (possible isoform).

References for Anti-C17orf81 antibody (ab87175)

ab87175 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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