Overview

  • Product nameAnti-C1orf187 antibody
    See all C1orf187 primary antibodies
  • Description
    Rabbit polyclonal to C1orf187
  • SpecificityAt least three isoforms of C1orf187 are known to exist; ab117452 will detect the two shorter isoforms. ab117452 is predicted to not cross-react with RILP.
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-P, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to 17 amino acids from the C terminal of Human C1orf187 (BAG80561).

  • Positive control
    • Rat cerebellum tissue lysate.
  • General notesAvoid repeated freeze thaw cycles and exposure to prolonged high temperatures.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab117452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
IHC-P Use at an assay dependent concentration.
ICC Use a concentration of 5 µg/ml.

Target

  • FunctionChemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
  • Sequence similaritiesBelongs to the draxin family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGPA3119 antibody
    • Chromosome 1 open reading frame 187 antibody
    • Dorsal inhibitory axon guidance protein antibody
    • Dorsal repulsive axon guidance protein antibody
    • DRAXI_HUMAN antibody
    • Draxin antibody
    • FLJ34999 antibody
    • MGC117222 antibody
    • Neucrin antibody
    • OTTHUMP00000002262 antibody
    • UNQ3119 antibody
    see all

Anti-C1orf187 antibody images

  • Immunofluorescence of C1orf187 in mouse brain tissue with ab117452 at 20 ug/mL.
  • Anti-C1orf187 antibody (ab117452) at 1 µg/ml + Rat cerebellum tissue lysate at 15 µg

    Predicted band size : 38 kDa
  • Immunohistochemical analysis of mouse brain tissue, staining C1orf187 with ab117452 at 5 µg/ml.

References for Anti-C1orf187 antibody (ab117452)

ab117452 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"