Overview

  • Product nameAnti-C1orf19 antibody
    See all C1orf19 primary antibodies
  • Description
    Rabbit polyclonal to C1orf19
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Guinea pig, Cow, Cat, Dog, Human, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C-terminal amino acids 109-158 (

    ASLSHNRIREILKASRKLQGDPELPMSFTLAIVESDSTIVYYKLTDGFML

    ) of Mouse C1orf19 (NP_079953).

  • Positive control
    • Mouse Spleen lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab122934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionNon-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
  • Tissue specificityWidely expressed. Highly expressed in testis and uterus.
  • Sequence similaritiesBelongs to the SEN15 family.
  • Cellular localizationNucleus. Nucleus > nucleolus. May be transiently localized in the nucleolus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Chromosome 1 open reading frame 19 antibody
    • Chromosome 1 open reading frame 19, isoform CRA_c antibody
    • HsSen15 antibody
    • sen15 antibody
    • SEN15 homolog antibody
    • SEN15_HUMAN antibody
    • tRNA intron endonuclease Sen15 antibody
    • tRNA splicing endonuclease 15 homolog (S. cerevisiae) antibody
    • tRNA splicing endonuclease subunit Sen15 antibody
    • tRNA-intron endonuclease SEN15 antibody
    • tRNA-splicing endonuclease subunit SEN15 antibody
    • Tsen15 antibody
    see all

Anti-C1orf19 antibody images

  • Anti-C1orf19 antibody (ab122934) at 1 µg/ml + Mouse Spleen lysate at 10 µg

    Predicted band size : 19 kDa

References for Anti-C1orf19 antibody (ab122934)

ab122934 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"