Overview

  • Product name
    Anti-C1q antibody [JL-1] (Biotin)
    See all C1q primary antibodies
  • Description
    Mouse monoclonal [JL-1] to C1q (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: WB, IHC-Fr, ELISA, IHC-P, Functional Studiesmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    produced with immunization of C1q-/- C57BL/6 mice with purified mouse C1q.

  • Positive control
    • Spleen and kidney tissue of wild-type mice.

Properties

Applications

Our Abpromise guarantee covers the use of ab72355 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50. Predicted molecular weight: 26 kDa.
IHC-Fr 1/50. PubMed: 15343386
ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration. PubMed: 20484586
Functional Studies Use at an assay dependent concentration. JL-1 was administered to mice resulting in depletion of circulating C1q, glomerular deposition of C1q and induction of anti-C1q autoantibodies in susceptible mice.

Target

References

This product has been referenced in:
  • Tezel G  et al. Oxidative stress and the regulation of complement activation in human glaucoma. Invest Ophthalmol Vis Sci 51:5071-82 (2010). IHC-P ; Human . Read more (PubMed: 20484586) »
  • Li M  et al. Development of a humanized C1q A chain knock-in mouse: assessment of antibody independent beta-amyloid induced complement activation. Mol Immunol 45:3244-52 (2008). ELISA ; Mouse . Read more (PubMed: 18400300) »

See all 3 Publications for this product

Customer reviews and Q&As

Thank you for your enquiry.

It is possible the antibody may have been affected by this freezing. However, it is difficult to say how significant this would be. I can suggest it is still worth using the antibody as it is very possible it will...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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