Anti-C1QC antibody [EPR2984Y] (ab75756)


  • Product nameAnti-C1QC antibody [EPR2984Y]
    See all C1QC primary antibodies
  • Description
    Rabbit monoclonal [EPR2984Y] to C1QC
  • Tested applicationsSuitable for: WB, IP, IHC-P, ICC, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in human C1q (subunit C)

  • Positive control
    • Human plasma lysate and human liver tissue.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.


Associated products


Our Abpromise guarantee covers the use of ab75756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 26 kDa (predicted molecular weight: 26 kDa).
IP 1/10.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC 1/250 - 1/500.
Flow Cyt 1/50.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.


  • FunctionC1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
  • Involvement in diseaseDefects in C1QC are a cause of complement component C1q deficiency (C1QD) [MIM:613652]. A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.
  • Sequence similaritiesContains 1 C1q domain.
    Contains 1 collagen-like domain.
  • Post-translational
    O-linked glycans consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI385742 antibody
    • C1Q C antibody
    • C1qc antibody
    • C1QC_HUMAN antibody
    • C1QG antibody
    • Complement C1q subcomponent subunit C antibody
    • Complement component 1, q subcomponent, C chain antibody
    • complement component 1, q subcomponent, gamma polypeptide antibody
    see all

Anti-C1QC antibody [EPR2984Y] images

  • ab75756 at 1/100 dilution staining C1q in human liver by Immunohistochemistry, Paraffin-embedded tissue.
  • Anti-C1QC antibody [EPR2984Y] (ab75756) at 1/1000 dilution + human plasma lysate at 10 µg

    goat anti-rabbit HRP at 1/2000 dilution

    Predicted band size : 26 kDa
    Observed band size : 26 kDa

References for Anti-C1QC antibody [EPR2984Y] (ab75756)

ab75756 has not yet been referenced specifically in any publications.

Product Wall

The Anti-C1QC antibody [EPR2984Y] (ab75756) is a tissue culture supernatant antibody. I can confirm that tissue culture tissue supernatant contains not only the pure antibody, but also other proteins and we do not regularly determine those concentratio...

Read More