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Product name Anti-C1r antibody See all C1r primary antibodies
Rabbit polyclonal to C1r
Tested applications Suitable for:
WB more details
Predicted to work with:
Non Human Primates
Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human C1r.
(Peptide available as
This antibody gave a positive signal in Human plasma (total protein)
Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 80 kDa).
Function C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Sequence similarities Belongs to the peptidase S1 family. Contains 2 CUB domains. Contains 1 EGF-like domain. Contains 1 peptidase S1 domain. Contains 2 Sushi (CCP/SCR) domains.
Post-translational modifications The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Information by UniProt
C1 R antibody
Anti-C1r antibody images
Western blot - C1r antibody (ab66751)
All lanes : Anti-C1r antibody (ab66751) at 1 µg/ml Lane 1 : Human Plasma Total Protein Lysate at 2 µg Lane 2 : Human Plasma Total Protein Lysate at 5 µg Lane 3 : Human Plasma Total Protein Lysate at 10 µg Secondary Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) Performed under reducing conditions. Predicted band size : 80 kDa Observed band size : 90 kDa ( why is the actual band size different from the predicted?) Exposure time : 1 minute
References for Anti-C1r antibody (ab66751)
This product has been referenced in:
et al. Periodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S, which Encode Subcomponents C1r and C1s of Complement. Am J Hum Genet 99:1005-1014 (2016).
Read more (PubMed: 27745832) »
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for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"