Overview

  • Product nameAnti-C1s antibody
    See all C1s primary antibodies
  • Description
    Rabbit polyclonal to C1s
  • Tested applicationsSuitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from a region corresponding to internal residues of Human C1s

  • Positive control
    • COLO, Jurkat cells and Human breast carcinoma tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+),150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab92706 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IHC-P
  • Application notesELISA: 1/40000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Predicted molecular weight: 77 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionC1s B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
    • Involvement in diseaseDefects in C1S are the cause of complement component C1s deficiency (C1SD) [MIM:613783]. A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.
    • Sequence similaritiesBelongs to the peptidase S1 family.
      Contains 2 CUB domains.
      Contains 1 EGF-like domain.
      Contains 1 peptidase S1 domain.
      Contains 2 Sushi (CCP/SCR) domains.
    • Post-translational
      modifications
      The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
    • Information by UniProt
    • Database links
    • Alternative names
      • Basic proline rich peptide IB 1 antibody
      • C1 esterase antibody
      • C1S antibody
      • C1S_HUMAN antibody
      • Complement C1s subcomponent antibody
      • Complement C1s subcomponent heavy chain antibody
      • Complement C1s subcomponent light chain antibody
      • Complement component 1 s subcomponent antibody
      • Complement component 1 subcomponent s antibody
      • FLJ44757 antibody
      see all

    Anti-C1s antibody images

    • All lanes : Anti-C1s antibody (ab92706) at 1/500 dilution

      Lane 1 : COLO cells (without peptide)
      Lane 2 : Jurkat cells (without peptide)
      Lane 3 : COLO cells (with peptide)

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 77 kDa
    • ab92706 at 1/50 dilution, staining C1s in Human breast carcinoma paraffin-embedded tissue by immunohistochemistry. Right hand image with peptide and left hand image without peptide.

    References for Anti-C1s antibody (ab92706)

    ab92706 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92706.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"