Recombinant Anti-EDEM2 antibody [EPR14043-24] (ab180522)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR14043-24] to EDEM2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-EDEM2 antibody [EPR14043-24]
See all EDEM2 primary antibodies -
Description
Rabbit monoclonal [EPR14043-24] to EDEM2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment within Human EDEM2 aa 450 to the C-terminus. The exact sequence is proprietary.
Database link: Q9BV94 -
Positive control
- HepG2 and IM9 cell lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituent: 59% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR14043-24 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab180522 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 65 kDa (predicted molecular weight: 65 kDa).
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 65 kDa (predicted molecular weight: 65 kDa). |
Target
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Function
Involved in endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. -
Tissue specificity
Expressed ubiquitously in all tissues tested with slightly higher levels detected in small intestine and peripheral blood leukocytes and weakest levels in brain and skeletal muscle. -
Sequence similarities
Belongs to the glycosyl hydrolase 47 family. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Secreted. Endoplasmic reticulum lumen. - Information by UniProt
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Database links
- Entrez Gene: 55741 Human
- Omim: 610302 Human
- SwissProt: Q9BV94 Human
- Unigene: 720177 Human
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Alternative names
- bA4204.1 antibody
- C20orf31 antibody
- C20orf49 antibody
see all
Images
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Anti-EDEM2 antibody [EPR14043-24] (ab180522) at 1/2000 dilution + IM9 cell lysate at 20 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 65 kDa -
Anti-EDEM2 antibody [EPR14043-24] (ab180522) at 1/10000 dilution + HepG2 cell lysate at 20 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 65 kDa
Datasheets and documents
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Datasheet download
Certificate of Compliance
References (0)
ab180522 has not yet been referenced specifically in any publications.