• Product nameAnti-C3 / C3a antibody [2898]
    See all C3 / C3a primary antibodies
  • Description
    Mouse monoclonal [2898] to C3 / C3a
  • SpecificityThis antibody reacts with the C-terminus of C3a. It reacts with intact C3 as with C3a.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to amino acids


    of C3/ C3a (last nine amino acids of C3a-desArg).

  • Positive control
    • Human plasma


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notes0.2 µm filtered
  • ClonalityMonoclonal
  • Clone number2898
  • IsotypeIgG1
  • Research areas


Our Abpromise guarantee covers the use of ab11874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: Use at an assay dependent dilution. Predicted molecular weight: 187.2 kDa.
    The starting working dilution is 1/10.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceComplement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptable to bacteria infection.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • Acylation stimulating protein antibody
      • AHUS5 antibody
      • ARMD9 antibody
      • ASP antibody
      • C3 and PZP like alpha 2 macroglobulin domain containing protein 1 antibody
      • C3 antibody
      • Complement C3 alpha chain antibody
      • Complement C3 antibody
      • Complement component 3 antibody
      • Complement component C3 antibody
      • Complement factor 3 antibody
      • CPAMD1 antibody
      • Plp antibody
      see all

    Anti-C3 / C3a antibody [2898] images

    • All lanes : Anti-C3 / C3a antibody [2898] (ab11874) at 1/200 dilution

      Lane 1 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate
      Lane 2 : Human liver tissue lysate - total protein (ab29889)

      Lysates/proteins at 10 µg per lane.

      Goat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Predicted band size : 187.2 kDa
      Observed band size : 187 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 115 kDa,71 kDa (possible cleavage fragment). We are unsure as to the identity of these extra bands.

    References for Anti-C3 / C3a antibody [2898] (ab11874)

    This product has been referenced in:
    • Ecker SM  et al. Aqueous cytokine and growth factor levels do not reliably reflect those levels found in the vitreous. Mol Vis 17:2856-63 (2011). WB ; Human . Read more (PubMed: 22128233) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry and I'm sorry to hear that your customer is experiencing difficulty with this antibody. Without knowing more details about what your customer has already tried, I would suggest trying the primary at 1:500 and optimizing from ...

    Read More

    The antibodies our source has in their product range gave only one option for setting up an immunoassay to quantify complement C3a, but this option will also recognize C3. The option is: ab11874: monoclonal antibody to human C3/C3a (C-terminus, clo...

    Read More