Overview

  • Product name
    Anti-C3a Receptor antibody
    See all C3a Receptor primary antibodies
  • Description
    Rabbit polyclonal to C3a Receptor
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Non human primates, Macaque monkey, Orangutan
  • Immunogen

    Recombinant fragment, corresponding to amino acids 1-209 of Human C3a Receptor.

  • Positive control
    • A549 whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab126250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 54 kDa. Optimal working dilutions should be determined experimentally by the user
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
  • Tissue specificity
    Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AZ 3B antibody
    • AZ3B antibody
    • C3a anaphylatoxin chemotactic receptor antibody
    • C3A R antibody
    • C3A R1 antibody
    • C3a-R antibody
    • C3AR antibody
    • C3AR_HUMAN antibody
    • C3AR1 antibody
    • C3R1 antibody
    • Complement component 3 receptor 1 antibody
    • Complement component 3a receptor 1 antibody
    • HNFAG09 antibody
    see all

Images

  • Anti-C3a Receptor antibody (ab126250) at 1/3000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size: 54 kDa



    10% SDS-PAGE
  • ab126250, at 1/500 dilution, staining paraffin-embedded colon ca by immunohistochemical analysis

References

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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