Anti-C3a Receptor antibody [hC3aRZ1] (ab59554)

Overview

  • Product name
    Anti-C3a Receptor antibody [hC3aRZ1]
    See all C3a Receptor primary antibodies
  • Description
    Mouse monoclonal [hC3aRZ1] to C3a Receptor
  • Specificity
    This antibody recognizes the receptor for human complement component C3a (C3aR) (55kD)
  • Tested applications
    Suitable for: IHC-Fr, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human) C3a Receptor

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    Purified from tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    hC3aRZ1
  • Myeloma
    x63-Ag8.653
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab59554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
Flow Cyt
  • Application notes
    Flow Cyt: 1/10 - 1/20. Use 10µl of the sugested working dilution to label 1x106 cells in 100µl.
    IHC-Fr: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
    • Tissue specificity
      Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family.
    • Post-translational
      modifications
      Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AZ 3B antibody
      • AZ3B antibody
      • C3a anaphylatoxin chemotactic receptor antibody
      • C3A R antibody
      • C3A R1 antibody
      • C3a-R antibody
      • C3AR antibody
      • C3AR_HUMAN antibody
      • C3AR1 antibody
      • C3R1 antibody
      • Complement component 3 receptor 1 antibody
      • Complement component 3a receptor 1 antibody
      • HNFAG09 antibody
      see all

    References

    ab59554 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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