Overview

  • Product name
  • Description
    Rabbit polyclonal to C3IP1
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus
  • Immunogen

    Synthetic peptide corresponding to a region between amino acids 150-200 of Human C3IP1 (NP_067646.1).

  • Positive control
    • HeLa whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab101994 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
    • Tissue specificity
      Highly expressed in testis and at lower levels in the submandibular salivary gland.
    • Sequence similarities
      Contains 1 BTB (POZ) domain.
      Contains 6 Kelch repeats.
    • Domain
      The BTB domain is required for interaction with CUL3.
    • Information by UniProt
    • Database links
    • Alternative names
      • C3IP1 antibody
      • CUL3 interacting protein 1 antibody
      • CUL3-interacting protein 1 antibody
      • DKIR antibody
      • DKIR homolog antibody
      • FLJ27152 antibody
      • hDKIR antibody
      • Kelch like 12 (Drosophila) antibody
      • Kelch like 12 antibody
      • Kelch like 12 variant antibody
      • Kelch like protein 12 antibody
      • Kelch like protein C3IP1 antibody
      • kelch-like family member 12 antibody
      • Kelch-like protein 12 antibody
      • KLH12_HUMAN antibody
      • KLHL 12 antibody
      • klhl12 antibody
      • OTTHUMP00000038799 antibody
      see all

    Images

    • ab101996 at 1 µg/ml staining C3IP1 in HeLa cell lysate immunoprecipitated using ab101994 at 3 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with an exposure time of 30 seconds

    References

    ab101994 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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