Overview

  • Product nameAnti-C4 binding protein antibody
    See all C4 binding protein primary antibodies
  • Description
    Mouse monoclonal to C4 binding protein
  • SpecificityReacts with recombinant protein used as immunogen
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human C4 binding protein (AAH05378, 1 a.a. ~ 252 a.a) full-length recombinant protein with a tag.

  • Positive control
    • immunogen

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab76505 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 67 kDa.
    This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionControls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
    • Sequence similaritiesContains 3 Sushi (CCP/SCR) domains.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • C4b binding protein beta chain antibody
      • C4b-binding protein beta chain antibody
      • C4BP antibody
      • C4BPB antibody
      • C4BPB_HUMAN antibody
      • Complement component 4 binding protein beta antibody
      • Complement component 4 binding protein beta chain antibody
      • Complement component 4-binding protein beta antibody
      • OTTHUMP00000034288 antibody
      • OTTHUMP00000034289 antibody
      • OTTHUMP00000034375 antibody
      • OTTHUMP0000003474 antibody
      • Proline rich protein antibody
      • PRP antibody
      see all

    Anti-C4 binding protein antibody images

    • Anti-C4 binding protein antibody (ab76505) at 5 µg/ml + Immunogen at 0.2 µg

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

      Predicted band size : 67 kDa
      Observed band size : 48 kDa (why is the actual band size different from the predicted?)

    References for Anti-C4 binding protein antibody (ab76505)

    ab76505 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab76505.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"