Anti-C5 / C5b antibody [568] (ab11879)

Overview

  • Product nameAnti-C5 / C5b antibody [568]
    See all C5 / C5b primary antibodies
  • Description
    Mouse monoclonal [568] to C5 / C5b
  • SpecificityThis antibody reacts with an epitope on C5 and on C5b.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Unfortunately, this information is considered to be commercially sensitive

Properties

Applications

Our Abpromise guarantee covers the use of ab11879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Use under non reducing condition. Predicted molecular weight: 188.3 kDa.

Target

  • RelevanceC5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • C5 antibody
    • Complement C5 antibody
    • Complement component 5 antibody
    • CPAMD4 antibody

References for Anti-C5 / C5b antibody [568] (ab11879)

ab11879 has not yet been referenced specifically in any publications.

Product Wall

ab11879 is only able to recognize whole C5 or C5b as the epitope lies in the C5b region. Therefore, there should not be any cross-reactivity with C5a.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"