Overview

  • Product name
    Anti-C5R1 antibody [10/92]
    See all C5R1 primary antibodies
  • Description
    Rat monoclonal [10/92] to C5R1
  • Tested applications
    Suitable for: IHC-P, IHC-Fr, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    rBL-2H3 transfected cells expressing Mouse C5R1.

  • Positive control
    • Mouse Kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab117579 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml.
IHC-Fr Use at an assay dependent concentration.
Flow Cyt 1/50 - 1/100. Use 10 ul of the suggested working dilution to label 1x106 cells in 100 ul.



ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANAPHYLATOXIN RECEPTOR antibody
    • C5a anaphylatoxin chemotactic receptor antibody
    • C5a anaphylatoxin receptor antibody
    • C5A antibody
    • C5a ligand antibody
    • C5a-R antibody
    • C5aR antibody
    • C5AR_HUMAN antibody
    • c5ar1 antibody
    • C5R1 antibody
    • CD88 antibody
    • CD88 antigen antibody
    • Complement component 5 receptor 1 antibody
    • Complement component 5 receptor 2 antibody
    • Complement component 5a receptor 1 antibody
    see all

Images

  • Immunohistochemical analysis of C5R1 expression in Formalin-Fixed, Paraffin-Embedded Mouse Kidney tissue sing 10 µg/ml ab117579.

References

This product has been referenced in:
  • Song D  et al. Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration. Mol Vis 23:210-218 (2017). IHC-Fr ; Mouse . Read more (PubMed: 28442885) »

See 1 Publication for this product

Customer reviews and Q&As



Antibody ab117579 was raised against cells expressing murine C5aR. I apologize we do not have this cell lysate available for sale.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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