Overview

  • Product name
    Anti-C5R1 antibody [20/70]
    See all C5R1 primary antibodies
  • Description
    Rat monoclonal [20/70] to C5R1
  • Specificity
    Clone 20/70 has been reported to block the binding of C5a to murine C5R1.
  • Tested applications
    Suitable for: Flow Cytmore details
    Unsuitable for: IHC-Fr
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    RBL-2H3 transfected cells expressing murine C5R1.

Properties

Applications

Our Abpromise guarantee covers the use of ab53224 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: 1/50 - 1/100. Use 10µl f the suggested dilution for 106 cells in 100µl.

    Is unsuitable for IHC-Fr.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family.
    • Post-translational
      modifications
      Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ANAPHYLATOXIN RECEPTOR antibody
      • C5a anaphylatoxin chemotactic receptor antibody
      • C5a anaphylatoxin receptor antibody
      • C5A antibody
      • C5a ligand antibody
      • C5a-R antibody
      • C5aR antibody
      • C5AR_HUMAN antibody
      • c5ar1 antibody
      • C5R1 antibody
      • CD88 antibody
      • CD88 antigen antibody
      • Complement component 5 receptor 1 antibody
      • Complement component 5 receptor 2 antibody
      • Complement component 5a receptor 1 antibody
      see all

    References

    ab53224 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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