Anti-C5R1 antibody [20/70] (Phycoerythrin) (ab53434)

Overview

  • Product name
    Anti-C5R1 antibody [20/70] (Phycoerythrin)
    See all C5R1 primary antibodies
  • Description
    Rat monoclonal [20/70] to C5R1 (Phycoerythrin)
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Specificity
    Blocks the binding of the C5a to murine CD88
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    RBL-2H3 transfected cells expressing murine C5aR.

Properties

Applications

Our Abpromise guarantee covers the use of ab53434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/1 - 1/10. Use 10µl of this concentration to label 106 cells in 100µl



ab136585-Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANAPHYLATOXIN RECEPTOR antibody
    • C5a anaphylatoxin chemotactic receptor antibody
    • C5a anaphylatoxin receptor antibody
    • C5A antibody
    • C5a ligand antibody
    • C5a-R antibody
    • C5aR antibody
    • C5AR_HUMAN antibody
    • c5ar1 antibody
    • C5R1 antibody
    • CD88 antibody
    • CD88 antigen antibody
    • Complement component 5 receptor 1 antibody
    • Complement component 5 receptor 2 antibody
    • Complement component 5a receptor 1 antibody
    see all

References

ab53434 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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