Anti-C5R1 antibody [W17/1] (ab11884)

Overview

  • Product nameAnti-C5R1 antibody [W17/1]
    See all C5R1 primary antibodies
  • Description
    Mouse monoclonal [W17/1] to C5R1
  • Tested applicationsSuitable for: IHC-P, Flow Cyt, IHC-Frmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    This information is considered to be commercially sensitive.

Properties

Applications

Our Abpromise guarantee covers the use of ab11884 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.
  • Application notesIs unsuitable for IP.
  • Target

    • FunctionReceptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
    • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
    • Post-translational
      modifications
      Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ANAPHYLATOXIN RECEPTOR antibody
      • C5a anaphylatoxin chemotactic receptor antibody
      • C5a anaphylatoxin receptor antibody
      • C5A antibody
      • C5a ligand antibody
      • C5a-R antibody
      • C5aR antibody
      • C5AR_HUMAN antibody
      • c5ar1 antibody
      • C5R1 antibody
      • CD88 antibody
      • CD88 antigen antibody
      • Complement component 5 receptor 1 antibody
      • Complement component 5 receptor 2 antibody
      • Complement component 5a receptor 1 antibody
      see all

    References for Anti-C5R1 antibody [W17/1] (ab11884)

    ab11884 has not yet been referenced specifically in any publications.

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    The formulation for this product has not changed. Recent tests showed thatab11884 can be stored at 4ºC as well as at -20ºC, this is why the storage information has been updated. In general the life timeof...

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    I have spoken to one of our scientists in the lab who advised me that to perform blocking experiments we always use the immunogen without its conjugation, therefore just the synthesized peptide should be suitable for your purpose. I was advised tha...

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    The antibody was raised against the first extracellular domain of the protein termed "topo_dom" on the SwissProt database which you can access via our datasheet. I hope this information helps, please let me know if you need more details,

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"