Anti-C5R1 (phospho S338) antibody (ab61022)

Overview

  • Product nameAnti-C5R1 (phospho S338) antibody
    See all C5R1 primary antibodies
  • Description
    Rabbit polyclonal to C5R1 (phospho S338)
  • Specificityab61022 detects endogenous levels of C5R1 only when phosphorylated at serine 338.
  • Tested applicationsSuitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic phosphopeptide derived from human C5R1 around the phosphorylation site of serine 338 (T-R-SP-T-V).

  • Positive control
    • Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab61022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
ELISA 1/40000.

Target

  • FunctionReceptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANAPHYLATOXIN RECEPTOR antibody
    • C5a anaphylatoxin chemotactic receptor antibody
    • C5a anaphylatoxin receptor antibody
    • C5A antibody
    • C5a ligand antibody
    • C5a-R antibody
    • C5aR antibody
    • C5AR_HUMAN antibody
    • c5ar1 antibody
    • C5R1 antibody
    • CD88 antibody
    • CD88 antigen antibody
    • Complement component 5 receptor 1 antibody
    • Complement component 5 receptor 2 antibody
    • Complement component 5a receptor 1 antibody
    see all

Anti-C5R1 (phospho S338) antibody images

  • Immunohistochemistry analysis of paraffin-embedded human brain tissue using ab61022 with (right) and without (left) the presence of the immunizing peptide.

References for Anti-C5R1 (phospho S338) antibody (ab61022)

ab61022 has not yet been referenced specifically in any publications.

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