Overview

  • Product nameAnti-C6 antibody - N-terminal
    See all C6 primary antibodies
  • Description
    Rabbit polyclonal to C6 - N-terminal
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the N terminal region of Human C6 conjugated to KLH.

  • Positive control
    • MDA-MB231 cell line lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab92622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 105 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionConstituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
    • Involvement in diseaseDefects in C6 are the cause of complement component 6 deficiency (C6D) [MIM:612446]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
    • Sequence similaritiesBelongs to the complement C6/C7/C8/C9 family.
      Contains 1 EGF-like domain.
      Contains 2 Kazal-like domains.
      Contains 1 LDL-receptor class A domain.
      Contains 1 MACPF domain.
      Contains 2 Sushi (CCP/SCR) domains.
      Contains 3 TSP type-1 domains.
    • Post-translational
      modifications
      All cysteine residues are assumed to be cross-linked to one another. Individual modules containing an even number of conserved cysteine residues are supposed to have disulfide linkages only within the same module.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • AW111623 antibody
      • C6 antibody
      • CO6_HUMAN antibody
      • Complement component 6 antibody
      • Complement component C6 antibody
      see all

    Anti-C6 antibody - N-terminal images

    • Anti-C6 antibody - N-terminal (ab92622) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

      Predicted band size : 105 kDa

    References for Anti-C6 antibody - N-terminal (ab92622)

    ab92622 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92622.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"