Overview

  • Product nameAnti-C7 antibody
    See all C7 primary antibodies
  • Description
    Rabbit polyclonal to C7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-843 of Human C7 (NP_000578.2).

  • Positive control
    • Mouse kidney whole cell lysate; C7 transfected 293 whole cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferpH: 7.4
    Constituent: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 93 kDa.

Target

  • FunctionConstituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.
  • Involvement in diseaseDefects in C7 are a cause of complement component 7 deficiency (C7D) [MIM:610102]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
  • Sequence similaritiesBelongs to the complement C6/C7/C8/C9 family.
    Contains 1 EGF-like domain.
    Contains 1 LDL-receptor class A domain.
    Contains 1 MACPF domain.
    Contains 2 Sushi (CCP/SCR) domains.
    Contains 2 TSP type-1 domains.
  • Post-translational
    modifications
    C7 has 28 disulfide bridges.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C7 antibody
    • CO7_HUMAN antibody
    • complement component 7 antibody
    • Complement component C7 antibody

Anti-C7 antibody images

  • Anti-C7 antibody (ab103621) at 1 µg/ml + Mouse kidney tissue lysate at 50 µg

    Predicted band size : 93 kDa
  • All lanes : Anti-C7 antibody (ab103621) at 1 µg/ml

    Lane 1 : C7 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 93 kDa
    Observed band size : 93.5 kDa (why is the actual band size different from the predicted?)

References for Anti-C7 antibody (ab103621)

ab103621 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"