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Cell-permeable, fast acting branched polymamine; selectively induces the growth of actin-enriched lamellipodia within minutes (at ~10-100 µM) without the need for serum cofactor by slowing down the actin assembly/disassembly cycle and facilitating nucleation. Has no effect when cellular actin polymerization is prevented by prior incubation with the depolymerizing drugs Cytochalasin D or Latrunculin A.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"