Overview

  • Product nameAnti-CA5B antibody
    See all CA5B primary antibodies
  • Description
    Rabbit polyclonal to CA5B
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 261-290 of Human CA5B.

  • Positive control
    • Mouse liver tissue lysate; human skeletal muscle

Properties

Applications

Our Abpromise guarantee covers the use of ab103091 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 36 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • RelevanceCA5B is a Carbonic anhydrase: a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA5B is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.
  • Cellular localizationMitochondrial
  • Database links
  • Alternative names
    • CA VB antibody
    • Carbonate dehydratase VB antibody
    • Carbonic anhydrase 5B, mitochondrial antibody
    • Carbonic anhydrase VB antibody
    • Carbonic anhydrase VB, mitochondrial antibody
    see all

Anti-CA5B antibody images

  • Anti-CA5B antibody (ab103091) at 1/50 dilution + Mouse liver lysate at 35 µg

    Predicted band size : 36 kDa
  • ab103091, at 1/50 dilution, staining CA5B in formalin-fixed, paraffin-embedded human skeletal muscle by Immunohistochemistry using a peroxidase conjugated secondary antibody and DAB staining.

References for Anti-CA5B antibody (ab103091)

ab103091 has not yet been referenced specifically in any publications.

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