Overview

  • Product nameAnti-CABYR antibody
    See all CABYR primary antibodies
  • Description
    Rabbit polyclonal to CABYR
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 93-142 (SKVPTQMEKS TDTDEDNVTR TEYSDKTTQF PSVYAVPGTE QTEAVGGLSS) of Human CABYR (NP_722454).

  • Positive control
    • HepG2 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab122951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.
  • Tissue specificityExpressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed in testis. Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors.
  • Sequence similaritiesContains 1 RIIa domain.
  • Post-translational
    modifications
    Isoform 1 is phosphorylated on tyrosine residues during in vitro capacitation. Isoform 3 and isoform 5 are phosphorylated by GSK3B in vitro. Dephosphorylation affects its ability to bind calcium.
  • Cellular localizationCytoplasm > cytoskeleton. Cell projection > cilium > flagellum. Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella and Nucleus. Cytoplasm. Cell projection > cilium > flagellum. According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.
  • Information by UniProt
  • Database links
  • Alternative names
    • CABYR antibody
    • CABYR_HUMAN antibody
    • Calcium binding tyrosine-(Y)-phosphorylation regulated antibody
    • Calcium-binding protein 86 antibody
    • Calcium-binding tyrosine phosphorylation-regulated protein antibody
    • Cancer/testis antigen 88 antibody
    • CBP86 antibody
    • CT88 antibody
    • Fibrousheathin II antibody
    • Fibrousheathin-2 antibody
    • FSP-2 antibody
    • FSP2 antibody
    • Testis-specific calcium-binding protein CBP86 antibody
    see all

Anti-CABYR antibody images

  • Anti-CABYR antibody (ab122951) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 24 kDa

References for Anti-CABYR antibody (ab122951)

ab122951 has not yet been referenced specifically in any publications.

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