Overview

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab28502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 66 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/62500.

Target

  • FunctionThe beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
  • Tissue specificityIsoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.
  • Sequence similaritiesBelongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
  • Cellular localizationCell membrane > sarcolemma.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAB1 antibody
    • CACB1_HUMAN antibody
    • CACNB1 antibody
    • CACNLB1 antibody
    • Calcium channel L type beta 1 polypeptide antibody
    • Calcium channel voltage dependent beta 1 subunit antibody
    • Calcium channel voltage-dependent subunit beta 1 antibody
    • CCHLB1 antibody
    • Dihydropyridine sensitive L type calcium channel beta 1 subunit antibody
    • MGC41896 antibody
    • Voltage dependent L type calcium channel beta 1 subunit antibody
    • Voltage-dependent L-type calcium channel subunit beta-1 antibody
    see all

Anti-CACNB1 antibody images



  • Predicted band size : 66 kDa
    Western Blot using ab28502 at 1.0ug/ml. Sample type: Hum. Adult Placenta Lysate


  • Predicted band size : 66 kDa
    Western Blot using ab28502 at 1.0ug/ml. Sample type: Hum. Fetal Heart Lysate


  • Predicted band size : 66 kDa
    Western Blot using ab28502 at 1.0ug/ml. Sample type: Hum. Fetal Liver Lysate


  • Predicted band size : 66 kDa
    Western Blot using ab28502 at 1.0ug/ml. Sample type: Hum. Fetal Lung Lysate


  • Predicted band size : 66 kDa
    Western Blot using ab28502 at 1.0ug/ml. Sample type: Hum. Fetal Muscle Lysate
  • Anti-CACNB1 antibody (ab28502) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate

    Secondary
    HRP conjugated anti-Rabbit IgG

    Predicted band size : 66 kDa
    Observed band size : 42 kDa (why is the actual band size different from the predicted?)
    Gel Concentration: 12%

References for Anti-CACNB1 antibody (ab28502)

This product has been referenced in:
  • Ruan B  et al. Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities. Proc Natl Acad Sci U S A 105:33-8 (2008). WB . Read more (PubMed: 18162540) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab28502.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"