Overview

  • Product name
    Anti-CACNG4 antibody
  • Description
    Rabbit polyclonal to CACNG4
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CACNG4 aa 154-183 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9UBN1

  • Positive control
    • K562 cells and lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab171143 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 37 kDa.
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Function
    Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
  • Sequence similarities
    Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CACNG4 antibody
    • Calcium channel voltage dependent gamma subunit 4 antibody
    • CCG4_HUMAN antibody
    • Neuronal voltage gated calcium channel gamma 4 subunit antibody
    • Neuronal voltage-gated calcium channel gamma-4 subunit antibody
    • TARP gamma-4 antibody
    • Transmembrane AMPAR regulatory protein gamma-4 antibody
    • Voltage dependent calcium channel gamma 4 subunit antibody
    • Voltage-dependent calcium channel gamma-4 subunit antibody
    see all

Images

  • Flow cytometric analysis of K562 cells labeling CACNG4 with ab171143 at 1/10 dilution (right histogram) compared to negative control cells (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

  • Anti-CACNG4 antibody (ab171143) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size: 37 kDa

References

ab171143 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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