Overview

  • Product nameAnti-CACNG4 antibody
    See all CACNG4 primary antibodies
  • Description
    Rabbit polyclonal to CACNG4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Zebrafish
  • Immunogen

    Synthetic peptide: IEGIYKGHCF RINHFPEDND YDHDSSEYLL RIVRASSVFP ILSTILLLLG , corresponding to N terminal amino acids 73-122 of Human CACNG4

  • Positive control
    • 721_B cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab80381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRegulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
  • Sequence similaritiesBelongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CACNG4 antibody
    • Calcium channel voltage dependent gamma subunit 4 antibody
    • CCG4_HUMAN antibody
    • Neuronal voltage gated calcium channel gamma 4 subunit antibody
    • Neuronal voltage-gated calcium channel gamma-4 subunit antibody
    • TARP gamma-4 antibody
    • Transmembrane AMPAR regulatory protein gamma-4 antibody
    • Voltage dependent calcium channel gamma 4 subunit antibody
    • Voltage-dependent calcium channel gamma-4 subunit antibody
    see all

Anti-CACNG4 antibody images

  • Anti-CACNG4 antibody (ab80381) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 36 kDa
    Observed band size : 36 kDa

References for Anti-CACNG4 antibody (ab80381)

ab80381 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Mouse Cell lysate - other (HeLa cells = -/+ transfected with CACNG4 ms frog o)
Gel Running Conditions Reduced Denaturing (12 % gel)
Loading amount 15 µg
Specification HeLa cells = -/+ transfected with CACNG4 ms frog o
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
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Submitted Jul 12 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"