Overview

  • Product name
    Anti-Cadherin like 23 antibody
    See all Cadherin like 23 primary antibodies
  • Description
    Rabbit polyclonal to Cadherin like 23
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment within Human Cadherin like 23 (C terminal). The exact sequence is proprietary. 250 aa of C-terminal
    Database link: Q9H251

Properties

Applications

Our Abpromise guarantee covers the use of ab192498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 369 kDa.

Target

  • Relevance
    Cadherin like 23 (or Cadherin 23) is, like other members of the cadherin family, a calcium-dependent cell adhesion glycoprotein that preferentially interacts with itself in connecting cells. It is a single pass type I membrane protein that contains 27 cadherin domains. Cadherin like 23 is expressed in the neurosensory epithelium, where it is thought to be involved in stereocilia organisation and hair bundle formation. Defects in the gene encoding Cadherin like 23 are a cause of Usher syndrome, which is characterised by profound congenital sensorineural deafness and eventual blindness. Mutations in this gene are also a cause of non-syndromic sensorineural deafness autosomal recessive type 12 (DFNB12). Cadherin like 23 has also been associated with age-related hearing loss.
  • Cellular localization
    Cell membrane; Single-pass type I membrane protein
  • Database links
  • Alternative names
    • Age related hearing loss 1 antibody
    • Ahl 1 antibody
    • Ahl antibody
    • Ahl1 antibody
    • Bob antibody
    • Bobby antibody
    • Bus antibody
    • Bustling antibody
    • Cadherin 23 antibody
    • Cadherin23 antibody
    • CDH 23 antibody
    • Mdfw antibody
    • Modifier of deaf waddler antibody
    • nmf112 antibody
    • nmf181 antibody
    • nmf252 antibody
    • Otocadherin antibody
    • USH 1D antibody
    • USH1 D antibody
    • USH1D antibody
    • Waltzer antibody
    see all

References

ab192498 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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