Overview

  • Product nameAnti-Cadherin like 23 antibody
    See all Cadherin like 23 primary antibodies
  • Description
    Goat polyclonal to Cadherin like 23
  • Specificityab81981 is expected to recognize both reported isoforms (NP_071407.3; NP_443068.1).
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    C-YNISLYENVTVGTS

    , corresponding to internal sequence amino acids 465-478 of Human Cadherin like 23 (NP_071407.3; NP_443068.1)

  • Positive control
    • Human Brain (Amygdala and Frontal Cortex) lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab81981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesPeptide ELISA: Antibody detection limit dilution 1/1000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 59 kDa (predicted molecular weight: 59 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceCadherin like 23 (or Cadherin 23) is, like other members of the cadherin family, a calcium-dependent cell adhesion glycoprotein that preferentially interacts with itself in connecting cells. It is a single pass type I membrane protein that contains 27 cadherin domains. Cadherin like 23 is expressed in the neurosensory epithelium, where it is thought to be involved in stereocilia organisation and hair bundle formation. Defects in the gene encoding Cadherin like 23 are a cause of Usher syndrome, which is characterised by profound congenital sensorineural deafness and eventual blindness. Mutations in this gene are also a cause of non-syndromic sensorineural deafness autosomal recessive type 12 (DFNB12). Cadherin like 23 has also been associated with age-related hearing loss.
    • Cellular localizationCell membrane; Single-pass type I membrane protein
    • Database links
    • Alternative names
      • Age related hearing loss 1 antibody
      • Ahl 1 antibody
      • Ahl antibody
      • Ahl1 antibody
      • Bob antibody
      • Bobby antibody
      • Bus antibody
      • Bustling antibody
      • Cadherin 23 antibody
      • Cadherin23 antibody
      • CDH 23 antibody
      • Mdfw antibody
      • Modifier of deaf waddler antibody
      • nmf112 antibody
      • nmf181 antibody
      • nmf252 antibody
      • Otocadherin antibody
      • USH 1D antibody
      • USH1 D antibody
      • USH1D antibody
      • Waltzer antibody
      see all

    Anti-Cadherin like 23 antibody images

    • Anti-Cadherin like 23 antibody (ab81981) at 1 µg/ml + Human Amygdala lysate (in RIPA buffer) at 35 µg
      Developed using the ECL technique

      Predicted band size : 59 kDa
      Observed band size : 59 kDa

    References for Anti-Cadherin like 23 antibody (ab81981)

    ab81981 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab81981.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"