Overview

  • Product nameAnti-Cadherin like 23 antibody
    See all Cadherin like 23 primary antibodies
  • Description
    Rabbit polyclonal to Cadherin like 23
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 287-336 (DYISGVLTLN GLLDRENPLY SHGFILTVKG TELNDDRTPS DATVTTTFNI) of Human Cadherin like 23 (NP_443068; UniProt ID: Q9H251 isoform 5).

  • Positive control
    • OVCAR3 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceCadherin like 23 (or Cadherin 23) is, like other members of the cadherin family, a calcium-dependent cell adhesion glycoprotein that preferentially interacts with itself in connecting cells. It is a single pass type I membrane protein that contains 27 cadherin domains. Cadherin like 23 is expressed in the neurosensory epithelium, where it is thought to be involved in stereocilia organisation and hair bundle formation. Defects in the gene encoding Cadherin like 23 are a cause of Usher syndrome, which is characterised by profound congenital sensorineural deafness and eventual blindness. Mutations in this gene are also a cause of non-syndromic sensorineural deafness autosomal recessive type 12 (DFNB12). Cadherin like 23 has also been associated with age-related hearing loss.
  • Cellular localizationCell membrane; Single-pass type I membrane protein
  • Database links
  • Alternative names
    • Age related hearing loss 1 antibody
    • Ahl 1 antibody
    • Ahl antibody
    • Ahl1 antibody
    • Bob antibody
    • Bobby antibody
    • Bus antibody
    • Bustling antibody
    • Cadherin 23 antibody
    • Cadherin23 antibody
    • CDH 23 antibody
    • Mdfw antibody
    • Modifier of deaf waddler antibody
    • nmf112 antibody
    • nmf181 antibody
    • nmf252 antibody
    • Otocadherin antibody
    • USH 1D antibody
    • USH1 D antibody
    • USH1D antibody
    • Waltzer antibody
    see all

Anti-Cadherin like 23 antibody images

  • Anti-Cadherin like 23 antibody (ab98059) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR3 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 59 kDa

References for Anti-Cadherin like 23 antibody (ab98059)

ab98059 has not yet been referenced specifically in any publications.

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