Anti-Calcitonin antibody [SP17], prediluted (ab27606)

Overview

  • Product nameAnti-Calcitonin antibody [SP17], prediluted
    See all Calcitonin primary antibodies
  • Description
    Rabbit monoclonal [SP17] to Calcitonin, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Horse, Dog, Pig
  • Immunogen

    Synthetic peptide: MGFQKFSPFL ALSILVLLQ A GSLHAAPF RS A, corresponding to amino acids 1-32 of Human Calcitonin.

  • Positive control
    • Thyroid or medullary carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab27606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready to use for 10 min at room temperature. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceCalcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
    • Cellular localizationCytoplasmic and Secreted
    • Database links
    • Alternative names
      • Alpha CGRP antibody
      • alpha type CGRP antibody
      • CALC 1 antibody
      • CALC A antibody
      • CALC1 antibody
      • calcitonin 1 antibody
      • calcitonin gene related peptide 1 antibody
      • calcitonin gene related peptide I antibody
      • calcitonin related polypeptide alpha antibody
      • CGRP 1 antibody
      • CGRP antibody
      • CGRP I antibody
      • CGRP1 antibody
      • CT antibody
      • katacalcin antibody
      • KC antibody
      see all

    Anti-Calcitonin antibody [SP17], prediluted images

    • Ab27606, prediluted, staining Calcitonin in formail fixed paraffin embedded human thyroid tissue sections by Immunohistochemistry.

    References for Anti-Calcitonin antibody [SP17], prediluted (ab27606)

    ab27606 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"