Overview

  • Product name
    Anti-Calcitonin receptor antibody
    See all Calcitonin receptor primary antibodies
  • Description
    Rabbit polyclonal to Calcitonin receptor
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Rat Calcitonin receptor.

    (Peptide available as ab93306.)

  • Positive control
    • This antibody gave a positive signal in the following tissue lysates: Mouse small intestine; Rat kidney.

Properties

Applications

Our Abpromise guarantee covers the use of ab83297 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 65 kDa (predicted molecular weight: 60 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.
    • Sequence similarities
      Belongs to the G-protein coupled receptor 2 family.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Calcitonin receptor antibody
      • Calcitonin receptor precursor antibody
      • CALCR antibody
      • CALCR_HUMAN antibody
      • CRT antibody
      • CT R antibody
      • CT-R antibody
      • CTR antibody
      • CTR1 antibody
      see all

    Images

    • All lanes : Anti-Calcitonin receptor antibody (ab83297) at 1 µg/ml

      Lane 1 : Small Intestine (Mouse) Tissue Lysate
      Lane 2 : Kidney (Rat) Tissue Lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 60 kDa
      Observed band size : 65 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 5 minutes

    References

    This product has been referenced in:
    • Hughes S  et al. Expression and localisation of two-pore domain (K2P) background leak potassium ion channels in the mouse retina. Sci Rep 7:46085 (2017). IHC-Fr ; Mouse . Read more (PubMed: 28443635) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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