Anti-Calcium binding protein P22 antibody (ab56953)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab56953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRequired for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1.
    • Tissue specificityUbiquitously expressed. Has been found in fetal eye, lung, liver, muscle, heart, kidney, thymus and spleen.
    • Sequence similaritiesContains 4 EF-hand domains.
    • Post-translational
      modifications
      Both N-myristoylation and calcium-mediated conformational changes are essential for its function in exocytic traffic.
      Phosphorylated; decreased phosphorylation is associated with an increase in exchange activity. The phosphorylation state may regulate the binding to NHE1.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Calcineurin B homolog antibody
      • Calcineurin B homologous protein antibody
      • Calcineurin homologous protein antibody
      • Calcium binding protein CHP antibody
      • Calcium binding protein p22 antibody
      • Calcium-binding protein CHP antibody
      • Calcium-binding protein p22 antibody
      • chp antibody
      • CHP1_HUMAN antibody
      • Sid 470 antibody
      • Sid470 antibody
      • SLC9A1 binding protein antibody
      • SLC9A1BP antibody
      • Wrch2 antibody
      see all

    Anti-Calcium binding protein P22 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56953 Calcium binding protein P22 antibody at 1ug/ml. Predicted band size of immunogen is 33 kDa

    References for Anti-Calcium binding protein P22 antibody (ab56953)

    ab56953 has not yet been referenced specifically in any publications.

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