Anti-Calcium binding protein P22 antibody (ab96203)

Overview

  • Product name
    Anti-Calcium binding protein P22 antibody
    See all Calcium binding protein P22 primary antibodies
  • Description
    Rabbit polyclonal to Calcium binding protein P22
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 47-111 of Human Calcium binding protein P22.

  • Positive control
    • HepG2 cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab96203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 22 kDa.

Target

  • Function
    Required for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1.
  • Tissue specificity
    Ubiquitously expressed. Has been found in fetal eye, lung, liver, muscle, heart, kidney, thymus and spleen.
  • Sequence similarities
    Contains 4 EF-hand domains.
  • Post-translational
    modifications
    Both N-myristoylation and calcium-mediated conformational changes are essential for its function in exocytic traffic.
    Phosphorylated; decreased phosphorylation is associated with an increase in exchange activity. The phosphorylation state may regulate the binding to NHE1.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Calcineurin B homolog antibody
    • Calcineurin B homologous protein antibody
    • Calcineurin homologous protein antibody
    • Calcineurin like EF hand protein 1 antibody
    • Calcium binding protein CHP antibody
    • Calcium binding protein p22 antibody
    • Calcium-binding protein CHP antibody
    • Calcium-binding protein p22 antibody
    • chp antibody
    • CHP1_HUMAN antibody
    • Sid 470 antibody
    • Sid470 antibody
    • SLC9A1 binding protein antibody
    • SLC9A1BP antibody
    • Wrch2 antibody
    see all

Images

  • Anti-Calcium binding protein P22 antibody (ab96203) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 22 kDa

References

ab96203 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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